With RayStation®*, your reirradiation workflow is simplified. Now with Plan + Prior treatment dose and optimization based on EQD2 for proton and light ions, the dose is automatically deformed to the new treatment image.
Reirradiation support
With the upcoming RayStation v2026*, RaySearch introduces enhanced support for reirradiation planning and evaluation. The new framework includes cumulative dose assessment based on deformable image registration and equieffective dose in 2 Gy fractions (EQD2). The framework enables ROI‑specific EQD2 parameters, including the modeling of partial tissue recovery between treatment courses.
Because reirradiation is fundamentally constrained by cumulative dose to organs at risk (OARs), particle therapy is particularly well suited for these scenarios. Its ability to reduce unnecessary dose to previously irradiated tissues helps mitigate the risk of severe toxicity, even in complex reirradiation cases. Reflecting this, RayStation supports reirradiation planning across modalities – including all currently supported delivery techniques for proton, helium, and carbon ion therapy – regardless of the modality used in prior treatments.
To further strengthen particle therapy in reirradiation, RayStation enables robust optimization of cumulative EQD2, allowing direct consideration of prior OAR doses in the optimization process. This can be combined with conventional robust optimization for the reirradiation target, accounting only for the dose contribution from the current plan. Together, these capabilities support a balanced and clinically relevant trade‑off between cumulative OAR doses and target coverage.
*Subject to regulatory clearance in some markets. RayStation v2026 is not available for use or sale in the USA or Canada. Functionality available can differ depending on scope of regulatory clearance, refer to your local vendor for available functionality in your country.
New Webinar Series!
Join us for Episode 2 of the RAYSEARCH WEBINARS: ADVANCING REIRRADIATION SERIES
🔥Episode 2: Reirradiation in RayStation®*: Insights from a multicenter study on cumulative dose evaluation and EQD2 optimization**
📅 2 November | 16:00 CET
REGISTER HERE
In this webinar, a multidisciplinary team from The Newcastle upon Tyne Hospitals NHS Foundation Trust will share insights from a multicenter reirradiation study using RayStation® for cumulative dose evaluation and exploring EQD2 optimization.
🗣️ Hear directly from the experts behind the study:
✦ Maha Zarroug — Medical Doctor and Clinical Oncologist | Clinical Perspective, Lung
✦ Nick West — Clinical Scientist | Lead Presenter & Study Representative
✦ Malcolm Jackson — Consultant Clinical Oncologist | Clinical Perspective, Head & Neck
✦ Nick Willis — Principal Dosimetrist and Head of Treatment Planning | Treatment Planning Perspective
Expect insights from the multicenter study, real-world examples from the presenting center, and a live Q&A.
*Subject to regulatory clearance in some markets.
** This functionality is investigational, not CE‑marked or FDA‑cleared, and is not available for clinical use.
RECORDED WEBINARS IN THE ADVANCING REIRRADIATION SERIES :
🔥Episode 1: Reirradiation in RayStation®: Planning with cumulative EQD2 in 3D*
Together with experts from RaySearch and Leeds Teaching Hospitals NHS Trust, we explored how the upcoming RayStation®* version supports cumulative EQD2 evaluation and optimization for reirradiation planning*, including clinical case demonstrations* and a lively Q&A session.
📽️ This webinar remains available on demand and can be viewed below.
📖 We have also compiled all questions raised during the webinar and their corresponding answers, which you can access here.
Reirradiation Challenges and Solutions Stina Svensson - RaySearch Webinars ASTRO 2025 Edition
This webinar explores the advancements and challenges in re-irradiation planning within radiotherapy, highlighting the increasing need for retreatments due to improved patient outcomes and more precise treatment options. The session covers technical complexities such as dose accumulation, deformable image registration, and the integration of biological planning tools, with insights into ongoing research collaborations and upcoming software releases aimed at enhancing clinical practice.