RaySearch at ESTRO 2026

16–18 MAY | STOCKHOLM, SWEDEN | BOOTH #C14:45

ONLINE ADAPTIVE – UNLEASHED BY SOFTWARE

With RayStation®, online adaptive replanning is fast, predictable, and user friendly. And with RayCare®, it connects into a single workflow platform, vendor-neutral and built for automation. So you can keep your linac. And simply choose RayStation and RayCare.

A MAJOR MILESTONE IN ADAPTIVE RADIOTHERAPY

RaySearch Laboratories is proud to announce that Iridium Netwerk in Belgium has successfully completed its first online adaptive radiation treatment on a Varian TrueBeam®** using RayStation®* and RayCare®*, demonstrating how truly adaptive treatments can now be delivered on widely installed linear accelerators.

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Online Adaptive radiotherapy functionality is not cleared or approved for sale or clinical use in the United States or Canada. Availability in other markets is subject to applicable regulatory approvals and varies by region.

** Varian and TrueBeam are trademarks owned by Varian Medical Systems, Inc., a Siemens Healthineers Company.

EXPLORE OUR SOLUTIONS AT ESTRO

Our solutions are more than just lines of code – they shape raw energy into life-saving cancer treatments.
Explore what's on demo and book some time with our experts below to discover the latest innovations in comprehensive cancer care.

DEMO LIST BOOK A DEMO

Our Expertise-Driven Community at ESTRO

At ESTRO, industry experts have a platform to share insights, express innovative ideas, and engage in active discussions – where every voice counts in shaping the future of advanced cancer care.

Immerse yourself in the expertise-driven community with us. Engage with the discussions at RayHub, get inspired at our Online Adaptive for the Masses Lunch Symposium, explore the latest advancements in our software, and connect over our shared vision of Innovating Radiation Oncology, Together.

ONLINE ADAPTIVE FOR THE MASSES

13:00–13:20 | Johan Löf
Founder and CEO, RaySearch Laboratories Stockholm, Sweden
Adaptive Planning: At the Heart of RaySearch

13:20–13:40 | Dr Susan Lalondrelle
Clinical Oncologist, Royal Marsden Hospital and Institute of Cancer Research, London, United Kingdom
Bringing Adaptive Radiotherapy to the Heart of Every Clinic

13:40–14:00 | Geert De Kerf
Medical Physics Expert, Iridium Netwerk, Wilrijk PhD candidate, University of Antwerp, Belgium
RayVolution in oART, From Concept to Treatment Delivery

RAYHUB

Immerse yourself in our expertise-driven community at RayHub, our dedicated in-booth space for learning and leading together.

Take a look at the agenda below!

Saturday, 16 May

10:00-10:30
PANEL: Personalized Cancer Care: When and How to Adapt?

Geert De Kerf, Medical Physics Expert, Iridium Netwerk
Danny Schuring, Medical Physicist, Radiotherapiegroep
Christian Richter, Head of Medical Physics, OncoRay - National Center of Radiation Research in Oncology

Moderated by: Stina Svensson, Senior Research Engineer, and Bie De Ost, RayCare Clinical Specialist, RaySearch Laboratories

13:00-13:30
Reirradiation: From Challenges to Solutions

Ane Appelt, Professor of Clinical Medical Physics, Rigshospitalet & Technical University of Denmark
Rasmus Bokrantz, Head of Algorithm Development, RaySearch Laboratories

Moderated by: Jakob Ödén, Research Engineer, RaySearch Laboratories

14:00-14:30
From Plan to Proof in Upright Particle Therapy

Stephen Towe, CEO, Leo Cancer Care
Christina Vallgren, CEO and Co-Founder, TERAPET SA
Erik Traneus, Research Engineer, RaySearch Laboratories

15:00-15:30
PANEL: Standardize the Process, Customize the Plan: Finding the Balance in Radiotherapy

Esther Troost, Radiation Oncologist, Universitätsklinikum Dresden
Jakob Liermann, Radiation Oncologist, Universitätsklinikum Heidelberg
Erik Engwall, Head of Physics, RaySearch Laboratories
Fredrik Löfman, Director of Machine Learning, RaySearch Laboratories

Moderated by: Morta Marcinkutė, Strategic Product Manager, RaySearch Laboratories

Sunday 17 May

10:00-10:30
PANEL: From Adoption to Accountability: How Do We Govern AI in Radiotherapy?

Ana Barragán Montero, Research Associate / Associate Professor, UCLouvain / FNRS
Charlotte Brouwer, Lead medical Physicist, University Medical Center Groningen
Michele Zeverino, PhD - Medical Physicist, Lausanne - CHUV
Fredrik Löfman, Director of Machine Learning, RaySearch Laboratories

Moderated by: Morta Marcinkutė, Strategic Product Manager, RaySearch Laboratories

11:30-12:00
Affordable Healthcare Through Cutting-Edge Technology

Reza Mohammadi, Product Manager, BEBIG Medical
Laura Antonovic, Strategic Partnerships Manager, RaySearch Laboratories

Monday 18 May

10:00-10:30
End-to-end workflow support in RayCare

Carolin Riddersporre, Project Manager Development, RaySearch Laboratories
Bie De Ost, Clinical Specialist, RaySearch Belgium

11:30-12:00
Brachytherapy planning: future perspectives

Tom Niessen, Technical Product Manager, RaySearch Laboratories

OUR EXPERTS AT ESTRO

This year, we are very happy to have submited a record number of abstracts on RaySearch initiated studies. Take a look at the latest from our Research and Development teams, and make sure to catch their sessions at ESTRO!

Brachytherapy

Robust optimization accounting for organ motion uncertainty in brachytherapy - Proffered Paper

Robust optimization and evaluation using simulated organ motion for brachytherapy, with comparison to clincal and inverse plan. Improved robustness when using robust optimization. Authors: Lovisa Byman, Tom Niessen, Rasmus Bokrantz, Erik Engwall

Fully automatic applicator image alignment in cervical brachytherapy treatment planning - Poster Highlight

Development and evaluation of an automatic applicator registration algorithm. The applicator is located and segmented in the MRI volume, which is registered with the 3D model. Evaluated on 50 images. Authors: Jakob Petterson, Tom Niessen, Ola Weistrand, Lovisa Byman

Interdisciplinary

Scenario exploration using automatic patient scheduling: A tool for radiation therapy resource optimization - Poster Highlight

Presentation of the RayScheduler simulation tool as a tool to aid resource allocation by allowing exploration of hypothetical clinic changes. Example showing how adding or removing one linac affects the patient waiting time. Authors: Ivar Bengtsson, Sophie Wuyckens, Geert De Kerf, Elin Hynning, Albin Fredriksson, Viktor Wase

Evaluating the impact of hypofractionation on patient waiting times at a Belgian hospital via automated scheduling scenario exploration - Poster Highlight

Using the RayScheduler simulation tool to quantify how much shorter waiting times different groups of patients would get if hypofractionation was introduced for prostate patients. Author: Sophie Wuyckens, Ivar Bengtsson, Geert De Kerf, Elin Hynning, Albin Fredriksson, Viktor Wase

Physics

Probabilistic optimization for systematic and random uncertainties in radiation therapy - Digital Poster

A new probabilistic optimization framework aiming to fulfil goals in, e.g., 90% of the scenarios. Dose computation by interpolation in a grid of precomputed doses allows for fast calculation of full treatment course doses. Authors: Albin Fredriksson, Erik Engwall, Jenneke de Jong, Johan Sundström

Shoot-through enhanced proton arcs for stereotactic radiosurgery of brain metastases - Poster Highlight

Proton arcs in combination with shoot-through layers can outperform VMAT with multi-target beam setup. Without shoot-through layers VMAT is better. Authors: Johan Sundström, Erik Engwall

Evaluation of novel robustness strategies in lattice proton arc therapy employing translationally invariant dose patterns and shoot-through layers - Poster Discussion

Lattice therapy is a form of spatially fractionated radiotherapy (SFRT) to treat bulky tumors. A new robust optimization technique is proposed. Shoot-through layers can also play a role for lattice. Authors: Erik Engwall, Albin Fredriksson, Johan Sundström, Gian Guyer, Rémy Kinj, David Patin, Agnes Angerud

Biological adaptive radiotherapy: how to overcome varying hypoxia in particle therapy - Mini Oral

Automatic replanning based on hypoxia level. Authors: Lars Glimelius, Gustav Lidberg, Elis Coniavitis, Vittoria Pavanello

Parameter-specific doses as a way to handle ambiguous biologically weighted doses in the RayStation treatment planning system - Digital Poster

Presentation of the parameter-specific dose concept that allows us to resolve the ambiguity in biological dose due to dose-grid discretization for structures with different parameters. With EQD2 examples of a prostate case. Authors: Elias Coniavitis, Rasmus Bokrantz, Jakob Ödén, Daniel Simon Colomar, Gustav Lidberg, Lars Glimelius

Can target partitioning reduce valley-to-peak dose for SFRT lattice VMAT? - Digital Poster

Followed a published lattice optimization protocol (for Eclipse) to create a standard VMAT, a target partitioning VMAT and a target partitioning SWO plan. Target partitioning gave lower valleys in the cranio-caudial plane but not in the transversal compared to equivalent VMAT with manually selected collimator angles (part of protocol). Authors: Agnes Angerud, Johan Sundström

Optimizing dynamic collimator rotation to improve dose conformity in photon arc therapy - Digital Poster

Evaluation of dynamic collimator rotation for multimets and an irregularly shaped lung tumor. Dynamic rotation resulted in improved gradient indices and reduced dose bridges. Authors: Paulina Treskog, Johan Sundström, Albin Fredriksson

Fully automatic selection of vascular input function for dynamic contrast-enhanced (DCE) MRI applied to brain, head and neck, and prostate - Digital Poster

Automatically extracting a vascular input function regardless of anatomical site. Useful for computing quantitative parameter maps. Proposed algorithm is evaluated for brain, head and neck, and prostate data. Author: Teo Asplund

The effect of input uncertainty on the reproducibility of perfusion parameter maps - Digital Poster

Investigating the effect on computed quantitative perfusion parameter maps for different values of plausible estimated input values. Result was most sensitive to errors in T1 estimate, but errors in hematocrit, and timeshift also had an effect. Authors: Alicia Palmér, Teo Asplund, Bikash Panthi, Mohamad El-Jammal, Andrew Miller Elliott, Eleni Konstantinopoulou, Stina Svensson, Caroline Chung

RTT

Hybrid path planning for patient positioning robots - Poster Discussion

We present a novel path planning algorithm for patient positioning before external beam radiation therapy using a robotic couch. The approach combines a flexible nondeterministic planner for transporting patients close to the treatment position and a deterministic planner for controlled movements into treatment positions when close to the treatment head. The study is motivated by the clinical preference for a planner that is flexible enough to move the patient from various room positions, while simultaneously providing predictable movements around the treatment head. Authors: Jezdimir Milosevic, Patrik Malm, Hopfgartner Johannes, Rasmus Bokrantz

Fast collision detection integrated in treatment planning system improved using surface scans from CT simulation - Digital Poster

Comparison between performing collision detection using C-RAD patient surface scans, compared to representing patient arm geometry with cylinder ROI surrogate, using collision detection algorithm in RS. Authors: Alicia Palmér, Joachim Marichal, Ola Weistrand, Mattias Nilsing

A NIGHT WITH RAYSEARCH

We can’t wait to celebrate 25 years of innovation together with our users, partners, and friends in Stockholm's iconic stadshus, for what is set to be the party of the year!

This event is currently sold out so reach out to your RaySearch contact to get access to the waiting list.

At RaySearch, we believe that collaboration is the catalyst for innovation in cancer care. By partnering with industry leaders, we aim to create interoperable solutions that prioritize patient needs and empower healthcare providers with the tools they need.

We’re proud to continue our membership with UniteRT. If you haven’t heard of us, UniteRT is a collaboration of leading radiation therapy vendors that promotes open, vendor agnostic ecosystems.

At ESTRO, you’ll see that spirit in action on the floor of the congress hall. Because when the industry works together, clinics get more freedom, and patients benefit.

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